Changes in PKC gamma immunoreactivity in mouse hippocampus induced by spatial discrimination learning
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چکیده
منابع مشابه
Changes in PKCr lmmunoreactivity in Mouse Hippocampus Induced by Spatial Discrimination Learning
In the present study, we examined changes in immunoreactivity (ir) for the y-isoform of protein kinase C (PKC7) in mouse hippocampus in relation to spatial memory processes employing the monoclonal antibody 36G9 raised against purified PKC7. Learning and memory were assessed by performance in a free-choice spatial pattern paradigm in a hole board in which the animals learned the pattern of 4 ba...
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An immunocytochemical examination of the rabbit hippocampus was done to determine which of the Ca(2+)-dependent protein kinase C (PKC) isoforms (PKC alpha, -beta I, -beta II, or -gamma) are involved in associative learning. The hippocampally dependent trace eyeblink conditioning task was used for behavioral training, and pseudoconditioned and naive animals served as controls. Significant increa...
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Calcium signaling critical to neural functions is mediated through Ca(2+) channels localized on both the plasma membrane and intracellular organelles such as endoplasmic reticulum. Whereas Ca(2+) influx occurs via the voltage- or/and ligand-sensitive Ca(2+) channels, Ca(2+) release from intracellular stores that amplifies further the Ca(2+) signal is thought to be involved in more profound and ...
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ژورنال
عنوان ژورنال: The Journal of Neuroscience
سال: 1992
ISSN: 0270-6474,1529-2401
DOI: 10.1523/jneurosci.12-12-04808.1992